It also blocks inflammation via PGE-2 (Lorenzetti et al 1991). The cannabis sesquiterpenoid β-caryophyllene shows increasing promise in this regard.
With so many CBD products currently sold on the market, choosing the right formula to help ease your arthritis pain can be confusing. It is important to first understand the principle of bioavailability. The first controlled trial evaluating the application of cannabis-based medicine in RA treatment was conducted in 2006. After a five-week period, researchers concluded that the THC/CBD combination in Sativex produced significant improvements in pain on movement, pain at rest, and quality of sleep with very mild side effects. Hemp and marijuana are variations of the Cannabis Sativa plant.
Anxiety is often a component of pain, and CBD can help reduce the anxiety associated with pain by activating serotonin (sometimes known as the “happy hormone) pathways. CBD appears to reduce pain in both direct and indirect ways—a good thing, because that likely means that CBD can reduce different types of pain in arthritis and other diseases where joint pain is an issue. A recent study using an online survey of chronic pain patients indicated that use of CBD for osteoarthritis could reduce the use of opioids. A synthetic form of CBD was applied as a topical gel to treat knee pain in osteoarthritis. The results indicated that pain reduction was significant using the synthetic CBD gel.
We tested dozens of products amongst our staff, and through our network of RA readers and found Spruce CBD to be the most effective. The one you choose will depend largely on the location and severity of your pain. If you want to target a specific area, an oil or oil topical may be the best. However, if the pain is all over, then a tincture or dietary supplement may provide the most relief. Originally, marijuana use and sales became illegal under the Marijuana Tax Act of 1937, with this illegality continuing under the Controlled Substances Act.
Different cannabis plants — often called hemp or marijuana — contain different levels of chemical compounds. For example, CBD stops the body from absorbing anandamide, a compound associated with regulating pain.
Something other than Tylenol, aspirins and goody powders. For myself, other than aspirin all other NSAIDs are off the table for they make me incredibly sick. Tylenol and goody powders also come with great risks after years of use.